1.
Chem Commun (Camb)
; 60(28): 3810-3813, 2024 Apr 02.
Article
in English
| MEDLINE
| ID: mdl-38488056
ABSTRACT
A novel probe C1 combining benzothiazole with a spiropyran section was developed for the specific detection of human serum albumin (HSA). The molecular docking suggested that the sulphonic acid group modification allowed C1 to form specific hydrogen bonds with lysine (Lys137) at fatty acid site 1 (FA1) of HSA, thus enabling fluorescence differentiation between HSA and BSA.
Subject(s)
Serum Albumin, Bovine , Serum Albumin, Human , Humans , Serum Albumin, Human/chemistry , Serum Albumin, Bovine/chemistry , Fluorescent Dyes/chemistry , Molecular Docking Simulation , Fatty Acids , Spectrometry, Fluorescence , Protein Binding
2.
Chem Commun (Camb)
; 56(57): 7925-7928, 2020 Jul 21.
Article
in English
| MEDLINE
| ID: mdl-32529994
ABSTRACT
In situ self-assembled boronate ester comprising commercially available 2-formylphenylboronic acid and 2-(2',3'-bihydroxyphenyl)benzothiazole (BHBT) is explored for the detection of ONOO- with product-boosted fluorescence. The self-assembly can detect ONOO- in the endoplasmic reticulum of living cells.
